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Azulfidine Prescription

Azulfidine, an anti-inflammatory drug, is prescribed for the treatment of mild to moderate ulcerative colitis (a long-term, progressive bowel disease) and as an added treatment in severe ulcerative colitis (chronic inflammation and ulceration of the lining of large bowel and rectum, the main symptom of which is bloody diarrhea). This drug is also prescribed to decrease severe attacks of ulcerative colitis.

Azulfidine EN-tabs are prescribed for people with ulcerative colitis who cannot take the regular Azulfidine tablet because of symptoms of stomach and intestinal irritation such as nausea and vomiting when taking the first few doses of the drug, or for those in whom a reduction in dosage does not lessen the stomach or intestinal side effects. The EN-tabs are also prescribed for adults and children with rheumatoid arthritis who fail to get relief from salicylates (such as aspirin) or other nonsteroidal anti-inflammatory drugs (such as ibuprofen).

Although ulcerative colitis rarely disappears completely, the risk of recurrence can be substantially reduced by the continued use of Azulfidine.

Azulfidine Side Effects

- vomiting;
- stomach distress;
- rash;
- nausea;
- lack of appetite;
- itching;
- inflammation of the mouth;
- hives;
- headache;
- fever;
- bluish skin;
- anemia;
- abdominal pain;

Azulfidine Dosage

Your doctor will carefully individualize your dosage and monitor your response periodically.

ULCERATIVE COLITIS

Adults

The usual recommended initial dose of Azulfidine and Azulfidine EN-tabs is 3 to 4 grams daily divided into smaller doses (intervals between nighttime doses should not exceed 8 hours). In some cases the initial dosage is set at 1 to 2 grams daily to lessen side effects. As therapy continues, the dose is usually reduced to 2 grams daily.

Children Aged 6 and Older

The usual recommended initial dose is 40 to 60 mg per 2.2 pounds of body weight in each 24-hour period, divided into 3 to 6 doses. For the longer term, the dose is usually reduced to 30 mg per 2.2 pounds of body weight in each 24-hour period, divided into 4 doses.

RHEUMATOID ARTHRITIS

Adults

The usual dose of Azulfidine EN-tabs is 2 grams a day, divided into smaller doses. Your doctor may have you start with a lower dose, then raise the dosage to 3 grams after 12 weeks.

Children aged 6 and older

The typical recommended daily dosage is 30 to 50 mg per 2.2 pounds of body weight, up to a maximum of 2 grams, taken in 2 equally divided doses. To reduce the chance of digestive side effects and other reactions, the doctor will probably start with a fraction of the typical dose and build up to it over a period of weeks.