Carbidopa

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Carbidopa Prescription

Carbidopa is a controlled-release tablet that may be given to help relieve the muscle stiffness, tremor, and weakness caused by Parkinson's disease. It may also be given to relieve Parkinson-like symptoms caused by:
- Carbon monoxide poisoning;
- Encephalitis;
- Manganese poisoning;

Carbidopa contains two drugs, carbidopa and levodopa. The drug that actually produces the anti-Parkinson's effect is levodopa. Carbidopa prevents vitamin B6 from destroying levodopa, thus allowing levodopa to work more efficiently.

Parkinson's drugs such as Carbidopa relieve the symptoms of the disease, but are not a permanent cure.

There is also a regular, non-controlled-release form of Carbidopa, which is called Sinemet. Over a period of hours, Carbidopa, the controlled-release form, gives a smoother release of the drug than regular Sinemet. If you have been taking regular Sinemet, be aware that you may need a somewhat higher dosage of Carbidopa to get the same degree of relief. Your first morning dose of Carbidopa may take as much as an hour longer to start working than your first morning dose of regular Sinemet.

Carbidopa Side Effects

- uncontrollable twitching or jerking;
- nausea;
- hallucinations;
- confusion;

Carbidopa Dosage

Your doctor will tailor your individual dosage carefully, depending on your response to previous therapy and symptoms.

ADULTS

For patients with mild to moderate symptoms, the initial recommended dose is 1 tablet of Carbidopa taken 2 times a day.

Starting doses should be spaced out every 4 to 8 hours and then adjusted to each patient's individual response.

The usual long-term dose is 2 to 8 tablets per day, taken in divided doses every 4 to 8 hours during the waking day.

Higher doses and shorter intervals have been used, but are not usually recommended.

When doses of Carbidopa are given at intervals of less than 4 hours, and/or if the divided doses are not equal, it is recommended that the smaller doses be given at the end of the day.

An interval of at least 3 days between dosage adjustments is recommended.

Dosage adjustment of Carbidopa may be necessary if your doctor prescribes additional drugs.

CHILDREN

Use of Carbidopa in children under 18 is not recommended.


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