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Cozaar Prescription

Cozaar tablets contain the active ingredient losartan potassium, which is a type of drug called an angiotensin II antagonist. It works by preventing the action of a hormone in the body called angiotensin II.

Angiotensin II normally acts on special receptors in the body, with two main results. Firstly, it causes the peripheral blood vessels to narrow, and secondly, it stimulates the production of another hormone called aldosterone. Aldosterone causes salt and water to be retained by the kidneys, which increases the volume of fluid in the blood vessels.

Losartan blocks the receptors that angiotensin II acts on, and so prevents its actions. The main result of this is that the peripheral blood vessels are allowed to widen, which means that there is more space and less resistance in these blood vessels. This is the main mechanism by which the pressure in the blood vessels is lowered.

Blocking the actions of angiotensin II also reduces the action of aldosterone on the kidneys. The result of this is an increase in the amount of fluid removed from the blood by the kidneys. This decreases the amount of fluid in the blood vessels, which also lessens the resistance and pressure in the blood vessels.

The combined overall effect of these changes is to lower the blood pressure, hence losartan is prescribed to treat high blood pressure.

Losartan has been shown to reduce the risk of stroke in people who have high blood pressure together with an enlargement in the left side of their heart. People with both these conditions may therefore be prescribed losartan to reduce their chances of experiencing a stroke. However, Cozaar is not effective for this particular use in black patients.

Losartan has also been shown to delay the progression of kidney disease in people with type 2 diabetes who have related kidney complications. If you have diabetic kidney disease you may be prescribed losartan for this reason, regardless of whether or not you also have high blood pressure.

Why is Cozaar prescribed?

- delaying progression of kidney disease in people with type 2 diabetes and kidney complications;
- high blood pressure;
- reducing risk of stroke in people with high blood pressure and an enlarged heart;

Cozaar is prescribed in the treatment of high blood pressure. It is effective when prescribed alone or with other high blood pressure drugs, such as diuretics that help the body get rid of water.

Cozaar is also prescribed to slow the progress of kidney disease caused by type 2 diabetes. It is the first of a new class of blood pressure drugs called angiotensin II receptor antagonists. Cozaar works, in part, by preventing the hormone angiotensin II from constricting the blood vessels, which tends to raise blood pressure.

You must take Cozaar regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Cozaar, and you must continue taking it even if you are feeling well. Cozaar does not cure high blood pressure; it merely keeps it under control.

Cozaar can be taken with or without food.

Take it at the same time each day. For example, if you take the drug every morning before or after breakfast, you will establish a regular routine and be less likely to forget your dose.

Cozaar Side Effects

- upper respiratory infection;
- dizziness;
- weakness or loss of strength;
- severe swelling of lips face or tongue;
- rash or itching;
- pain in the muscles and joints;
- migraine;
- low red blood cell count or platelet count;
- low blood pressure;
- inflammation of the liver;
- high blood potassium level;
- fatigue;
- dizziness;
- diarrhoea;
- cough;
- balance problems involving the inner ear;
- alteration in results of liver function tests;
- cough;

Cozaar Dosage

ADULTS

High blood pressure

The usual starting dose is 50 mg once daily. However, Cozaar can also be taken twice daily, with total daily doses ranging from 25 mg to 100 mg. If your blood pressure does not respond within 3 to 6 weeks, your doctor may increase your dose or add a low-dose diuretic to your regimen.

For people taking diuretics and people with liver problems, the usual starting dose is 25 mg daily. Your doctor may adjust your dosage according to your response.

Kidney disease caused by diabetes

The usual starting dose is 50 mg once daily. The doctor may increase the dose to 100 mg once a day if blood pressure remains too high.

CHILDREN

The safety and effectiveness of Cozaar in children have not been studied.