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Glyburide Indications

Glyburide is an oral antidiabetic drug prescribed to treat type 2 diabetes, the kind that occurs when the body either does not make enough insulin or fails to use insulin properly. Insulin transfers sugar from the bloodstream to the body's cells, where it is then prescribed for energy.

There are two forms of diabetes: type 1 and type 2. Type 1 diabetes results from a complete shutdown of normal insulin production and usually requires insulin injections for life, while type 2 diabetes can usually be treated by dietary changes, exercise, and/or oral antidiabetic drugs such as Glyburide. This drug controls diabetes by stimulating the pancreas to produce more insulin and by helping insulin to work better. Type 2 diabetics may need insulin injections, sometimes only temporarily during stressful periods such as illness, or on a long-term basis if an oral antidiabetic drug fails to control blood sugar.

Glyburide can be prescribed alone or along with a drug called metformin if diet plus either drug alone fails to control sugar levels.

Glyburide Side Effects

- shallow breathing;
- seizures;
- pale skin;
- nervousness;
- nausea;
- nausea;
- heartburn;
- headache;
- fast heartbeat;
- drowsiness;
- coma;
- cold sweat;
- bloating;

Glyburide Dosage

ADULTS

Usually the doctor will prescribe an initial daily dose of 2.5 to 5 mg. Maintenance therapy usually ranges from 1.25 to 20 mg daily. Daily doses greater than 20 mg are not recommended. In most cases, Glyburide is taken once a day; however, people taking more than 10 mg a day may respond better to twice-a-day dosing.

CHILDREN

The safety and effectiveness of Glyburide have not been established in children.

OLDER ADULTS

Older, malnourished or debilitated individuals, or those with impaired kidney and liver function, usually receive lower initial and maintenance doses to minimize the risk of low blood sugar.