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Darunavir Indications

Darunavir belongs to a family of antiviral drugs known as protease inhibitors.
Darunavir belongs to a group of antiretroviral medicines known as protease inhibitors (PIs) and it is given alongside a number of other antiretrovirals in order to prevent your body from developing resistance to it.
Darunavir is an antiretroviral medicine which means that it is used in human immunodeficiency virus (HIV) infection.
Darunavir is indicated for the treatment of HIV infection. HIV is the virus that causes AIDS.
Darunavir is indicated for the treatment of human immunodeficiency virus (HIV) infection in antiretroviral treatment-experienced adult patients, such as those with HIV-1 strains resistant to more than one protease inhibitor.
Darunavir slows down the progress of HIV infection by reducing the amount of the virus in your body. This helps improve your immune system and reduces the risk of you developing the complications associated with HIV infection.
Darunavir slows the progress of HIV infection but it is not a cure.
Darunavir, in combination with with other antiretroviral agents, is specifically indicated for the treatment of HIV infection in antiretroviral treatment-experienced adult patients.

Darunavir Contraindications

Darunavir is contraindicated if you have any of the following conditions:
- If you are pregnant, trying for a baby or breast-feeding;
- If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines;
- If you have diabetes;
- If you have ever had an allergic reaction to this or to any other medicine This is particularly important if you know you are allergic to an antibacterial medicine known as a sulphonamide;
- If you have haemophilia (a bleeding disorder) or porphyria (a rare blood disorder);
- If you have hepatitis B or C;
- If you have liver problems;

Darunavir Interactions

Do not take Darunavir with any of the following drugs:
- TCA Antidepressants;
- Selective Serotonin Reuptake Inhibitors (SSRIs);
- PDE-5 inhibitors;
- Other HIV-Protease Inhibitors (PIs);
- Oral Contraceptives/estrogens;
- Nucleoside Reverse Transcriptase Inhibitors (NRTIs);
- Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs);
- Narcotic Analgesics;
- HMG-CoA Reductase Inhibitors: lovastatin, simvastatin;
- HMG-CoA Reductase Inhibitors;
- Herbal Products: St John's wort (Hypericum perforatum);
- H2-Receptor Antagonists and Proton Pump Inhibitors;
- Gastrointestinal Motility Agent: cisapride;
- Ergot Derivatives: dihydroergotamine, ergonovine, ergotamine, methylergonovine;
- Corticosteroids;
- Calcium Channel Blockers;
- Antimycobacterials;
- Antimycobacterial: rifampin;
- Anti-infectives;
- Antihistamines: astemizole, terfenadine;
- Antifungals;
- Anticonvulsants: carbamazepine, phenobarbital, phenytoin;
- Anticoagulants;
- Antiarrhythmics;

Darunavir Side Effects

Darunavir side effects that you should report to your health care professional or doctor as soon as possible:
- Body fat changes;
- Diarrhoea;
- Difficulty sleeping;
- Dizziness;
- Feeling bloated;
- Feeling or being sick;
- Headache;
- Joint aches and pain;
- Joint stiffness or difficulty moving;
- Numbness of the hands or feet;
- Pain in the abdomen;
- Tiredness;
- Wind;

Darunavir Overdose

Reported Darunavir overdose symptoms are:
- Nausea;
- Nasopharyngitis (cold symptoms);
- Headache;
- Diarrhea;

Darunavir Other Brand Names

In some countries Darunavir may also be known as:
- Prezista;