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Donepezil Indications

Donepezil works by increasing the amount of a natural chemical called acetylcholine in the brain, which is known to be lower in people suffering from dementia in Alzheimer's disease.
Donepezil is indicated to treat mild to moderate symptoms of dementia associated with Alzheimer's disease.
Donepezil is indicated to treat dementia associated with all stages of Alzheimer Disease (AD).
Donepezil is indicated to increase the amount of acetylcholine in the brain in patients with mild to moderate AD.
Donepezil is indicated in combination with another drug, memantine. Nemantine works differently than donepezil, and some people with AD benefit more from their combined use than either drug alone.
Donepezil is indicated for management of symptoms associated with Alzheimer's Disease.
Donepezil cannot cure dementia or Alzheimer's disease but it can slow down the progression of dementia and can help to ease the symptoms.
Although Donepezil helps control the symptoms of AD, it does not cure the disease.

Donepezil Contraindications

Donepezil is contraindicated if you have any of the following conditions:
- If you are pregnant, trying for a baby or breast-feeding;
- If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines;
- If you have ever had a stomach ulcer;
- If you have ever had an allergic reaction to this or to any other medicine;
- If you have liver problems;
- If you have lung problems such as asthma or chronic obstructive pulmonary disease (also known as COPD);

Donepezil Interactions

Do not take Donepezil with any of the following drugs:

Possible antagonism of action:
- Acepromazine;
- Aceprometazine;
- Alverine;
- Amantadine;
- Amitriptyline;
- Amoxapine;
- Atropine;
- Azatadine;
- Belladona;
- Benztropine;
- Biperiden;
- Brompheniramine;
- Carbinoxamine;
- Chlorpheniramine;
- Chlorpromazine;
- Chlorprothixene;
- Cimetidine;
- Clemastine;
- Clidinium;
- Clomipramine;
- Clozapine;
- Cyclizine;
- Cyclobenzaprine;
- Cyproheptadine;
- Darifenacin;
- Desipramine;
- Dexbrompheniramine;
- Dicyclomine;
- Dimenhydrinate;
- Diphenhydramine;
- Diphenoxylate;
- Diphenylpyraline;
- Disopyramide;
- Doxepin;
- Doxylamine;
- Ethopropazine;
- Flavoxate;
- Flupenthixol;
- Glutethimide;
- Glycopyrrolate;
- Hydroxyzine;
- Hyoscyamine;
- Imipramine;
- Isocarboxazid;
- Isopropamide;
- Loxapine;
- Maprotiline;
- Meclizine;
- Meperidine;
- Mesoridazine;
- Methdilazine;
- Methotrimeprazine;
- Methylscopolamine;
- Mirtazapine;
- Moclobemide;
- Molindone;
- Nortriptyline;
- Olanzapine;
- Orphenadrine;
- Oxybutynin;
- Perphenazine;
- Phenelzine;
- Phenindamine;
- Pheniramine;
- Pimozide;
- Pipotiazine;
- Procainamide;
- Prochlorperazine;
- Procyclidine;
- Promazine;
- Promethazine;
- Propantheline;
- Propericiazine;
- Protriptyline;
- Quetiapine;
- Quinidine;
- Quinidine barbiturate;
- Risperidone;
- Scopolamine;
- Scopolamine;
- Sertraline;
- Solifenacin;
- Thioproperazine;
- Thioridazine;
- Thiothixene;
- Tizanidine;
- Tolterodine;
- Tranylcypromine;
- Trazodone;
- Trifluoperazine;
- Triflupromazine;
- Trihexyphenidyl;
- Trimeprazine;
- Trimethobenzamide;
- Trimipramine;
- Tripelennamine;
- Triprolidine;
- Trospium;
- Trospium;
- Ziprasidone;
- Zuclopenthixol;

Donepezil Side Effects

Donepezil side effects that you should report to your health care professional or doctor as soon as possible:
- Abnormal dreams;
- Black or tarry stools;
- Bloody vomit (hematemesis);
- Changes in behavior;
- Chest pain;
- Confusion;
- Depression;
- Diarrhea;
- Diarrhoea;
- Difficulty falling asleep or staying asleep;
- Difficulty sleeping;
- Difficulty urinating or pain when urinating;
- Discoloration or bruising of the skin;
- Dizziness;
- Dizziness;
- Drowsiness;
- Excessive tiredness;
- Fainting;
- Falling;
- Feeling agitated or aggresive;
- Feeling faint;
- Feeling or being sick;
- Fever;
- Frequent urination;
- Hallucinations (seeing or hearing things not really there);
- Headache;
- Inability to control urination;
- Itching;
- Joint pain, swelling, or stiffness;
- Loss of appetite;
- Lower back pain;
- Muscle cramp;
- Muscle cramps;
- Nausea;
- Nervousness;
- Pain;
- Rash;
- Red blood in stools;
- Red, scaling, itchy skin;
- Seizures;
- Slow heartbeat;
- Tiredness;
- Urine incontinence;
- Vomiting;
- Weight loss;

Donepezil Overdose

Reported Donepezil overdose symptoms are:
- Bradycardia;
- Collapse;
- Convulsions;
- Hypotension;
- Low blood pressure, which can lead to fainting;
- Muscle weakness;
- Respiratory depression;
- Salivation;
- Severe nausea;
- Slow heart rate;
- Sweating;
- Vomiting;

Donepezil Other Brand Names

In some countries Donepezil may also be known as:
- Aricept;
- Eranz;
- Aricept ODT;