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Sirolimus Indications

Sirolimus is indicated to prevent organ rejection in patients receiving kidney transplants.
Sirolimus is indicated to prevent organ rejection in patients receiving kidney transplants.
Sirolimus is indicated in some types of cardiac stents as a coating around the expandable metal mesh its properties may provide advantages over the bare-metal type of stent.
Sirolimus is indicated for use in patients 13 years of age and older.
Sirolimus is indicated for the prophylaxis of organ rejection in patients receiving renal transplants.
Sirolimus belongs to a class of antibiotics and immunosuppressive drugs known as macrolides, all of which share a large lactone ring to which are attached one or more deoxy sugars.

Sirolimus Interactions

Do not take Sirolimus with any of the following drugs:
- Bromocriptione;
- Carbamazepine;
- Cimetidine;
- Cisapride;
- Clarithromycin;
- Clotrimazole;
- Cyclosporine;
- Danazol;
- Diltiazem;
- Erythromycin;
- Fluconazole;
- HIV-protease inhibitors (eg, ritonavir, indinavir);
- Itraconazole;
- Ketoconazole;
- Metoclopramide;
- Nicardipine;
- Phenobarbital;
- Phenytoin;
- Rifabutin;
- Rifampin;
- Rifapentine;
- St John's Wort (Hypericum perforatum);
- Telithromycin;
- Troleandomycin;
- Verapamil;
- Voriconazole;

Sirolimus Side Effects

Sirolimus side effects that you should report to your health care professional or doctor as soon as possible:
- Abdominal pain;
- Anemia (low red blood cell counts or hemoglobin levels);
- Arthralgia (joint aches);
- Constipation;
- Diarrhea;
- Fever;
- Headache;
- Hypercholesterolemia (high blood cholesterol levels);
- Hypertension;
- Hypertriglyceridemia (high blood lipid levels);
- Increased blood creatinine levels;
- Nausea;
- Pain;
- Peripheral edema (fluid retention/swelling in the limbs);
- Thrombocytopenia (low blood platelet counts);
- Urinary tract infection;

Sirolimus Other Brand Names

In some countries Sirolimus may also be known as:
- Rapamycin;
- Rapamune;